Science

Background Knowledge

Virucidal activity of disinfectants

Compared to bacteria, viruses still play an inferior role as elicitor of nosocomial infections – but they gain in importance. Hence, disinfectants should possess an appropriate virucidal activity. In 2004, the Robert Koch-Institute (RKI), the German Association for the Control of Virus Diseases (DVV) and the German Society for Hygiene and Microbiology (DGHM) regulated the marking of disinfectants’ virucidal activity with the terms “virucidal against enveloped viruses” and “virucidal”. “virucidal against enveloped viruses” promises the effect against all enveloped viruses, while “virucidal” promises the effect against enveloped and non-enveloped viruses, which are more difficult to inactivate. Test viruses were selected for both claims. If these viruses are inactivated within the limits of the specified tests, disinfectants carry the claim “virucidal against enveloped viruses” or “virucidal”.

In Germany, the nonenveloped adeno, polio, polyoma and vaccinia viruses were selected as test viruses for “virucidal” marking, and thus the efficacy against non-enveloped and enveloped viruses. For enveloped viruses, efficacy against BVDV (bovine viral diarrhea virus) and vaccinia virus has to be proven. On European level, the evidence of a virucidal activity is produced via adeno and polio viruses.
However, in practice a comprehensive virucidal activity of hand disinfectants is only necessary in certain situations, e.g. officially ordered decontaminations (in accordance with IfSG § 18) and due to proven existence of nonenveloped viruses.

Further information:

Only available in German

„Prüfung und Deklaration der Wirksamkeit von Desinfektionsmitteln gegen Viren“
Stellungnahme des Arbeitskreises Viruzidie beim Robert Koch-Institut (RKI)sowie des Fachausschusses „Virusdesinfektion “der Deutschen Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) und der Desinfektionsmittelkommission der Deutschen Gesellschaft für Hygiene und Mikrobiologie (DGHM)
(pdf-file)